Antisperm Immunity for Contraception
نویسندگان
چکیده
منابع مشابه
Optimized assay for antisperm cell-mediated immunity.
Previous studies on antisperm cell-mediated immunity (CMI) have been confounded by the presence of immunogenic leukocytes in sperm antigen preparations. In this study we isolated pure populations of viable spermatozoa on discontinuous Percoll gradients, and utilized sonicated and cavitated extracts, as well as live motile spermatozoa, to measure cellular immunity to spermatozoa in vasectomized ...
متن کاملCharacterization of fertility related antisperm antibodies- a step towards causal treatment of immunological infertility and immuno-contraception.
Antisperm antibodies (ASA) occur in men and women and may significantly impair fertility. The identification of functionally rele vant antigens of ASA is important for establishing causal treatment options on the one hand and may, on the other hand, enhance the de velopment of tools for immunocon traception. One candidate protein is addressed in an article of Wang et al. [1] published in Asi...
متن کاملAntisperm antibodies and fertility association.
OBJECTIVE To evaluate the relation between antisperm antibodies (ASA) and human fertility by reviewing the scientific literature of the last 45 years. METHODS We carried out a review of scientific literature about antisperm antibodies and infertility published in spanish or english in databases as Pubmed, Medline, Scielo, some books and another gray literature include information related to t...
متن کاملFrequency of Antisperm Antibodies in Infertile Women
BACKGROUND Infertility is one of the common problems seen in couples of reproductive age. Presence of antisperm antibodies in semen and serum are amongst the causes of immunoinfertility. This study was performed to determine antisperm antibodies in cervicovaginal secretions and serum of infertile women and also measure serum levels of immunoglobulins (IgG, IgM and IgA). METHODS The study cons...
متن کاملValidity of a rapid assay for antisperm antibodies in semen.
OBJECTIVE To determine the validity of a rapid assay for antisperm antibodies in semen. DESIGN Prospective comparison of the results of standard and rapid antisperm antibody assays performed simultaneously. SETTING Tertiary care infertility center. PATIENT(S) Couples who presented for infertility evaluation. INTERVENTION(S) Semen analysis and measurement of antisperm antibodies in semen...
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ژورنال
عنوان ژورنال: Journal of Andrology
سال: 2006
ISSN: 0196-3635
DOI: 10.2164/jandrol.05192